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Four questions that start from a species or a published dataset rather than from one genome's files. Each reads a table prepared once on this machine and then shared by every project on it. Several of them answer with no genome open at all.

Page What it answers
Transcription factors Which genes a species' published census calls transcription factors, and which are cofactors.
Motifs How to load a JASPAR release, scan sequence against it, and read the hits back.
Gene identifiers How to convert ids between databases, and how to match a symbol that was renamed.
Homology How Ensembl Compara links two species' genes, and how to resolve one species' ids into another's.

Anything that begins with one assembly's files is under Working with a genome.